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Onkologische Patienten mit einem Ileus

Interdisziplinäre Betreuung

Oncology patients with an ileus

Interdisciplinary treatment

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Zusammenfassung

Tumorpatienten mit einem Ileus stellen eine sehr heterogene Patientengruppe dar. Die Ätiologie ihres Ileus reicht von benignen Briden und Adhäsionen bis zur schwersten disseminierten Peritonealkarzinose. Patienten mit einem intra- oder auch extraabdominalen, in das Abdomen metastasierten Malignom (z. B. Mammakarzinom) können im weiteren Verlauf in bis zu 40% der Fälle einen Darmverschluss entwickeln. Die adäquate Betreuung von Tumorpatienten mit einem Ileus muss interdisziplinär erfolgen. Ziel sollte es sein, individuell für jeden Patienten die optimale kurative oder palliative Therapie zu finden, die es ermöglicht, mit einer geringen Morbidität und Letalität eine hohe Lebensqualität zu erreichen.

Abstract

In patients with a history of cancer the etiology of ileus is heterogeneous. Bowel obstruction may be caused by benign adhesion or severe generalized carcinomatosis. Approximately 40% of patients with intra-abdominal and extra-abdominal (e.g. breast cancer) malignancies will develop malignant bowel obstruction. The appropriate therapy of cancer patients with ileus can be difficult and should be managed by interdisciplinary cooperation. Benign reasons of bowel obstruction have to be operated immediately. Palliative care of patients with carcinomatosis must be tailored to the individual need of the patient. There are multiple treatment options. Palliative care selects ideally between operative, interventional or medical options that will maximize quality of life and minimize complications.

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Literatur

  1. Abbas SM, Merrie AEH (2007) Resection of peritoneal metastases causing malignant small bowel obstruction. World J Surg Oncol 5:122

    Article  PubMed  Google Scholar 

  2. Abbas SM, Bissett IP, Parry BR (2007) Oral water soluble contrast for the management of adhesive small bowel obstruction. Cochrane Database Syst Rev 3:CD004651

    PubMed  Google Scholar 

  3. Blair SL, Chu DZJ, Schwarz RE (2001) Outcome of palliative operations for malignant bowel obstruction in patients with peritoneal carcinomatosis from nongynecological cancer. Ann Surg Oncol 8:632–637

    Article  PubMed  CAS  Google Scholar 

  4. Branco BC, Barmparas G, Schnüringer B et al (2010) Systematic review and meta-analysis of the diagnostic and therapeutic role of water-soluble contrast agent in adhesive small bowel obstruction. Br J Surg 97:470

    Article  PubMed  CAS  Google Scholar 

  5. Catena F, Di Saverio S, Kelly MD et al (2011) Bologna guidelines for diagnosis and management of adhesive small bowel obstruction (ASBO): 2010 evidence-based guidelines of the World Society of Emergency Surgery. World J Emerg Surg 6:5

    Article  PubMed  Google Scholar 

  6. Chi DS, Phaëton R, Miner TJ et al (2009) A prospective outcomes analysis of palliative procedures performed for malignant intestinal obstruction due to recurrent ovarian cancer. Oncologist 14:835–839

    Article  PubMed  Google Scholar 

  7. Clark K, Lam L, Currow D (2009) Reducing gastric secretions – a role for histamine 2 antagonists or proton pump inhibitors in malignant bowel obstruction? Support Care Cancer 17:1463–1468

    Article  PubMed  CAS  Google Scholar 

  8. Fernández-Esparrach G, Bordas JM, Giráldez MD et al (2010) Severe complications limit long-term clinical success of self-expanding metal stents in patients with obstrutive colorectal cancer. Am J Gastroenterol 105:1087–1093

    Article  PubMed  Google Scholar 

  9. Frank P, Batzenschlager A, Philippe E (1990) Blind-pouch syndrome after side-to-side intestinal anastomosis. Chirurgie 116(8–9):586–596

    Google Scholar 

  10. Glockzin G, Schlitt HJ, Piso P (2009) Peritoneal carcinomatosis: patiens selection, perioperative complications and quality of life related to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. World J Surg Oncol 7:5

    Article  PubMed  Google Scholar 

  11. Hisanaga T, Shinjo T, Morita T et al (2010) Multicenter prospective study on efficacy and safety of octreotide for inoperable malignant bowel obstruction. Jpn J Clin Oncol 40(8):739–745

    Article  PubMed  Google Scholar 

  12. Hooft JE van, Bemelman WA, Oldenburg B et al (2011) Colonic stenting versus emergency surgery for acute left-sided malignant colonic obstruction: a multicentre randomised trial. Lancet Oncol 12:344–352

    Article  PubMed  Google Scholar 

  13. Kevans D, Smyth C, O’Brien C et al (2007) Reversible acute reactive arthritis secondary to iatrogenic blind loop syndrome. J Gastrointest Liver Dis 349

  14. Ly J, O’Grady G, Mittal A et al (2010) A systematic review of methods to palliative malignant gastric outlet obstruction. Surg Endosc 24:290–297

    Article  PubMed  Google Scholar 

  15. Miner TJ, Brennan MF, Jaques DP (2004) A prospective, symptom related, outcomes analysis of 1022 palliative procedures for advanced cancer. Ann Surg 240:719–727

    PubMed  Google Scholar 

  16. Pirlet IA, Slim K, Kwiatkowski F et al (2010) Emergency preoperative stenting versus surgery for acute left-sided malignant colonic obstruction: a multicenter randomized controlled trial. Surg Endosc 25(6):1814–1821

    Article  PubMed  Google Scholar 

  17. Ripamonti CI, Easson AM, Gerdes H (2008) Management of malignant bowel obstruction. Eur J Cancer 44:1105–1115

    Article  PubMed  Google Scholar 

  18. Sebastian S, Johnston S, Geoghegan T et al (2004) Pooled analysis of the efficacy and safety of self-expanding metal stenting in malignant colorectal obstruction. Am J Gastroenterol 99:2051–2057

    Article  PubMed  Google Scholar 

  19. Udomsawaengsup S, Brethauer S, Kroh M, Chand B (2008) Percutaneous transesophageal gastrostomy (PTEG): a safe and effective technique for gastrointestinal decompression in malignant obstruction and massive ascites. Surg Endosc 22:2314

    Article  PubMed  CAS  Google Scholar 

  20. Woolfson RG, Jennings K, Whalen GF (1997) Management of bowel obstruction in patients with abdominal cancer. Arch Surg 132:1093–1097

    PubMed  CAS  Google Scholar 

  21. Zorn M, Domagk D, Auerbach T et al (2010) Maligne intestinale Obstruktion. Z Gastroenterol 48:264–273

    Article  PubMed  CAS  Google Scholar 

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Holzer, K., Gog, C. & Trojan, J. Onkologische Patienten mit einem Ileus. Onkologe 17, 957–968 (2011). https://doi.org/10.1007/s00761-011-2099-4

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  • DOI: https://doi.org/10.1007/s00761-011-2099-4

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